Medical : Cardiology

Cardiac aging, like aging in general, is a complex process involving numerous cellular and molecular changes, which along the way contribute to the expression of the multiple phenotypes of aging, "the different faces" of cardiac aging. Several plausible theories have been considered to explain aging, e.g., evolution, free radical, somatic mutation, etc; and at this time it is most likely that these different theories are intertwined with each other without a definitive "winner," reflecting a mixture of genetic and epigenetic elements found in most aged individuals with cardiovascular defects. The demonstration in numerous animal models of the dramatic alterations in life-span achieved by gene engineering or dietary modifications, such as caloric restriction, further underscores the interplay of both genetic and environmental factors involved in aging, as well as acting through molecular and signaling pathways operative in the heart and the vasculature. Aging and decreasing heart function occurring together has been amply documented, and our knowledge of age associated cardiac pathologies has outpaced our understanding of the basic mechanisms underlying these processes. At present, genomics, proteomics and recombinant DNA techniques are increasingly applied to the study of cardiac cell structure and function. Their role in aging, in general, and in the aging heart, in particular, will finally be unveiled. With the availability of the Human Genome Project, and an ever increasing number of animal models and new and exciting molecular technologies, the unraveling of the underlying basic mechanisms of cardiac aging have already begun. In this book, the genetic and molecular basis ofcardiovascular aging will be discussed and a comprehensive assessment of the bioenergetics changes occurring in human and animal models of cardiac aging, current diagnostic and future therapeutic modalities will be presented. more...

Price: $179.00

The foremost guide on treatment regimens and preventive strategies for AIDS-related heart dysfunction. more...

Price: $199.95

Alcohol and Heart Disease investigates the effects of alcoholic beverage intake on human cardiac function, focusing on the pathological effects of high alcohol consumption as well as the potential benefits of moderate use. more...

Price: $94.95

Angina is most commonly associated with myocardial ischemia, but may also be symptomatic of valvular heart disease, hypertrophic cardiomyopathy or uncontrolled high blood pressure. While chronic or stable angina is predictable and relatively easy to manage, it is the sudden and unexpected onset of symptoms in patients with unstable angina that represents the most significant challenge to the clinician, being a risk indicator for acute MI, severe cardiac arrhythmia or even cardiac arrest. Since chest pain can also indicate a number of other less critical conditions, it is important that the clinician can rapidly and accurately determine the true risk status of the patient in each case.In this atlas, the authors guide the reader through the assessment of the patient with chest pain, beginning with the simple physical examination and evaluation of other risk factors that may be present, progressing to non-invasive tests such as EKG and various imaging techniques, and concluding with coronary angiography. The diagnostic value of each of these techniques is compared and appropriate guidance given on evaluating clinical findings. more...

Price: $99.95

Angiogenesis has been identified as a “common denominator” in society’s most serious diseases, and more than $4 billion has been invested in the research and development of angiogenesis-based medicines, making it one of the most heavily funded areas of medical research in history. more...

Price: $175.00